Join a fully remote study comparing a marine-derived collagen supplement with glucosamine–chondroitin to see how these supplements may support activity-related knee comfort and mobility in healthy adults.
The study begins with a 1-week screening phase. During this time, participants will connect a compatible wearable device (Apple watch, Fitbit, Garmin, Oura Ring, Whoop or GoogleFit) complete short daily knee-comfort ratings, and track activity for 7 days. Those who complete all screening activities will receive a $20 Amazon gift card. Participants who qualify will then be randomized to NT-II™ 240 mg, NT-II™ 480 mg, or glucosamine–chondroitin, taken once daily with food for 12 weeks. During the main study, you’ll complete weekly knee-comfort surveys, sync wearable data, and use the Curovate app to measure knee range of motion at the beginning and end of the study. Participants who complete all required activities in the main study will receive a $120 Amazon gift card.
Complete a short screening questionnaire through our online platform to confirm eligibility for the study. If eligible, you’ll review the study details and sign an electronic consent form through the Alethios platform.
During this 7-day screening phase, you’ll connect your wearable device and complete a short daily survey. Participants who meet adherence requirements will receive a $20 Amazon gift card, even if not enrolled in the main study.
After the research team reviews your results from the 7-day run-in period, you may be enrolled in the main study. If selected, you’ll confirm or deny your willingness to participate and complete knee range of motion measurements at baseline, week 6, and week 12, along with daily discomfort assessments.
After completing all study requirements, adherent participants will receive a $120 Amazon gift card and access to their individual study data.
NT-II™ is a marine-derived undenatured type II collagen. This study is testing whether taking NT-II™ daily can support knee comfort and mobility during activity, compared with glucosamine–chondroitin. Over 12 weeks, researchers will look at weekly knee-comfort ratings, wearable-captured activity metrics and knee range of motion.